Anti-mullerian hormone levels and chances for conception
Besides Clomiphene challenge test, Day 3 FSH (follicle stimulating hormone) and estradiol (E2) test, Blood levels of the hormone AMH are often used by fertility specialists as part of the evaluation of ovarian reserve.
There are some problems involved with interpretation of AMH hormone levels. Because the test has not been in routine use for many years, the levels considered to be "normal" are not yet clarified and agreed on by the experts. Also, not all current commercial assays give equivalent results.
AMH, or anti-mullerian hormone is a substance produced by granulosa cells in ovarian follicles. Production decreases and then stops as follicles grow. There is almost no AMH made in follicles over 8mm.
I have treated many patients with the condition. The recent one is a lady with FSH in 30s, Estrogen in 30s and AMH .16. After 3 month treatment, her FSH reduces to 12. Estrogen goes to 60s. and AMH 0.5.
The table below has AMH interpretation guidelines from the fertility literature. Do not get carried away with the cutoff values shown here. For example, the difference between a 0.6 and a 0.7 ng/ml test result puts a woman in a "different box" in this table - but there is very little real difference in fertility potential. In reality, it is a continuum - and not something that categorizes well.
Interpretation
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AMH Blood Level
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High (often PCOS)
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Over 3.0 ng/ml
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Normal
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Over 1.0 ng/ml
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Low Normal Range
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0.7 - 0.9 ng/ml
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Low
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0.3 - 0.6 ng/ml
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Very Low
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Less than 0.3 ng/ml
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