The researchers induced PCOS in rats using 5α-dihydrotestosterone (DHT) to determine whether or not electrical or manual acupuncture was superior in the regulation of menstruation. The rats received acupuncture five times per week for 4-5 weeks. The electroacupuncture group received 2 Hz stimulation at the acupuncture points. Untreated rats served as the control group.
The manual and electroacupuncture groups showed normalization of estrogen activity and a decrease in androgens. In addition, the electroacupuncture group showed changes in the central opioid receptors of the hypothalamus suggesting that electroacupuncture may be “mediated by central opioid receptors….” The manual acupuncture group showed changes in the steroid receptors of the hypothalamus suggesting that manual acupuncture “may involve regulation of steroid hormone/peptide receptors.”
Another study published in the American Journal of Physiology – Endocrinology and Metabolism concludes that low frequency electro-acupuncture improved menstrual frequency and balanced sex steroid levels in women with PCOS, polycystic ovarian syndrome.b This study measured blood changes in human female participants. Hyperandrogenism was measured in this study by determining the total concentration of testosterone, androgens, estrogens, androgen precursors, and glucuronidated androgen metabolites. The study measured that electro-acupuncture improved menstrual regularity in women with PCOS. The sex steroid levels in the electro-acupuncture group improved significantly and acne markedly decreased. The study measured improvements in a wide range of endocrine variables such that the researchers concluded that electro-acupuncture may help induce ovulation in women attempting to conceive since participants showed significant improvement in monthly menstrual frequency.
